Cerebral blood flow impairment and cognitive decline in heart failure

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Cognitive Impairment in Heart Failure

Cognitive impairment (CI) is increasingly recognized as a common adverse consequence of heart failure (HF). Although the exact mechanisms remain unclear, microembolism, chronic or intermittent cerebral hypoperfusion, and/or impaired cerebral vessel reactivity that lead to cerebral hypoxia and ischemic brain damage seem to underlie the development of CI in HF. Cognitive decline in HF is characte...

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Cerebral blood flow and neurological change in chronic heart failure.

In their article in this issue of Stroke, Gruhn et al report that cerebral blood flow (CBF) is reduced about 30% in patients with NYHA III/IV heart failure but has normalized when retested in 5 subjects 30 days after successful heart transplantation. The authors suggest that (1) the reduced CBF found before transplantation is responsible for neurological signs and symptoms reported in patients ...

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Cognitive impairment in heart failure patients

Cognitive damage in heart failure (HF) involves different domains thus interfering with the ability for single patient to self-care and to cope with treatment regimens, modifying symptoms and health behaviours. Many cerebral and functional changes were detected in brain imaging, involving areas of both grey and white matter deputed to cognition. Although various instruments are available to exp...

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Asymmetric Cerebral Blood Flow in Patients with Mild Cognitive Impairment: Possible Relationship to Further Cognitive Deterioration

AIM To explore patterns of cerebral blood flow in patients with mild cognitive impairment (MCI), who (1) eventually deteriorate into overt dementia, with no particular focus on the type of dementia, or (2) do not appear to further deteriorate in their cognitive functions. METHODS Thirty-seven MCI patients, with or without vascular pathology, were studied prospectively. The patients underwent ...

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ژورنال

عنوان ژورنال: Brain and Behavior

سال: 2021

ISSN: 2162-3279,2162-3279

DOI: 10.1002/brb3.2176